Haja Kadarmideen, Professor and Group Leader of Quantitative and Systems Genetics in the Department of Basic Animal and Veterinary Sciences, Faculty of Life Sciences, University of Copenhagen, will give a talk on Monday 5th September entitled: Unraveling The Missing Links in Genome-Phenome Axis by Systems Genetics. Time: 11.00 - 11.45
Place: UMB, Dept of Animal Sciences (IHA), meeting room lower ground floor ("Håkonshallen")
Systems genetics is a study of variations in DNA that impact complex phenotypic traits through micro-traits such as transcript, protein and metabolite abundance and other molecular pathways and networks. The talk will focus on introduction to and application of these systems genetics approaches in predicting individual genetic merit for quantitative traits or genetic risks for complex diseases and in development of biomarkers. Some examples of its application to gastro-intestinal nematode resistance in sheep, muscling in sheep, reproduction in mouse models and fertility in cattle will be illustrated. This talk will also outline 1) the ongoing project(s) in using pig as animal model for obesity and dogs as models for cardio-vascular diseases in human cohorts and 2) the use of biologically relevant information on SNP variants/candidate genes in improving accuracy of genomic selection. Collaboration in this discipline between the University of Copenhagen and the Norwegian University of Life Sciences will be open for discussion.
