Roger D. Cone is Professor of Molecular Physiology & Biophysics and Director of the Vanderbilt Institute for Obesity and Metabolism, Vanderbilt University Medical Center, Nashville, USA. The primary interest of the Cone lab is understanding how the central nervous system regulates energy stores. The group is focused not only on the normal process, but also on the pathophysiological mechanisms that lead to common obesity, severe monogenic obesity, metabolic syndrome, cachexia or disease wasting, anorexia nervosa, and other eating disorders. A theme of the lab has been understanding the role of the central melanocortin system in these processes. Because the lab is focused on a complex biological problem that impacts multiple physiological systems, a wide variety of techniques are applied, including genetics, molecular biology, neuroantomy, and electrophysiology. The work also spans a wide range of organisms, from zebrafish to mouse, to humans. New projects include development of the zebrafish as a model system for whole genome forward genetics of energy homeostasis, and identification of genes predisposing humans to anorexia nervosa.28 June: Regulation of somatic growth in teleosts
Roger D. Cone from the Vanderbilt University Medical Center will give a talk on Monday 28th June at 13.00 - 14.00 at UMB, Dept. of Animal Sciences, "Håkonshallen" seminar room on the lower ground floor, entitled: Regulation of somatic growth and background adaptation by the agouti related peptides in teleosts.
Roger D. Cone is Professor of Molecular Physiology & Biophysics and Director of the Vanderbilt Institute for Obesity and Metabolism, Vanderbilt University Medical Center, Nashville, USA. The primary interest of the Cone lab is understanding how the central nervous system regulates energy stores. The group is focused not only on the normal process, but also on the pathophysiological mechanisms that lead to common obesity, severe monogenic obesity, metabolic syndrome, cachexia or disease wasting, anorexia nervosa, and other eating disorders. A theme of the lab has been understanding the role of the central melanocortin system in these processes. Because the lab is focused on a complex biological problem that impacts multiple physiological systems, a wide variety of techniques are applied, including genetics, molecular biology, neuroantomy, and electrophysiology. The work also spans a wide range of organisms, from zebrafish to mouse, to humans. New projects include development of the zebrafish as a model system for whole genome forward genetics of energy homeostasis, and identification of genes predisposing humans to anorexia nervosa.
Roger D. Cone is Professor of Molecular Physiology & Biophysics and Director of the Vanderbilt Institute for Obesity and Metabolism, Vanderbilt University Medical Center, Nashville, USA. The primary interest of the Cone lab is understanding how the central nervous system regulates energy stores. The group is focused not only on the normal process, but also on the pathophysiological mechanisms that lead to common obesity, severe monogenic obesity, metabolic syndrome, cachexia or disease wasting, anorexia nervosa, and other eating disorders. A theme of the lab has been understanding the role of the central melanocortin system in these processes. Because the lab is focused on a complex biological problem that impacts multiple physiological systems, a wide variety of techniques are applied, including genetics, molecular biology, neuroantomy, and electrophysiology. The work also spans a wide range of organisms, from zebrafish to mouse, to humans. New projects include development of the zebrafish as a model system for whole genome forward genetics of energy homeostasis, and identification of genes predisposing humans to anorexia nervosa.
Project Coordinator
Recent Publications
- The weakly nonlocal limit of a one-population Wilson-Cowan model
- A vision and strategy for the virtual physiological human in 2010 and beyond
- The genotype-phenotype relationship in multicellular pattern-generating models - the neglected role of pattern descriptors
- Allele Interaction - Single Locus Genetics Meets Regulatory Biology
- Changes in lipid metabolism associated gene transcripts during porcine adipogenesis