John McEwan, principal scientist in animal genomics at AgResearch, will give a talk on Monday October 20, at the Norwegian University of Life Sciences (UMB) campus entitled: Sheep genome sequencing and SNP detection, development of a SNP chip, and its planned future use for genome wide selection in sheepTime: October 20, 10.00 - 11.00
Place: Håkonshallen, IHA, UMB
John C McEwan1 on behalf of International Sheep Genomics Consortium2
1AgResearch, Invermay Agricultural Centre PB 50034, Mosgiel, NZ
2http://www.sheephapmap.org
The sheep genome was "skim" sequenced to 3X coverage using 6 animals (Romney, Texel, Scottish Blackface, Merino, Dorset and Awassi). Our genome assembly is estimated to cover in excess of 42% of the ovine genome and represent 82% of the non repetitive fraction. This assembly also identified 277,000 high quality SNPs and additional reduced representational sequencing using Illumina's Genome Analyzer (Solexa® Sequencing Technology) on animals from 15 different breeds identified a further 76,000 high quality SNPs. 59,494 SNPs were selected for inclusion on a 50K+ Illumina Infinium iSelect(tm) SNP BeadChip, giving an average spacing of 46kb across the whole genome. A wide variety of breeds and a linkage mapping resource will be genotyped using this resource. Progress and interim results will be presented.
