Dag Inge VaageVåge, Dag Inge

Professor

E-mail: daginge.vage@umb.no

Phone: +47-6496-5281

Present positions: Professor in molecular genetics, Department of Animal- and Aquacultural Sciences / CIGENE, Norwegian University of Life Sciences

Degrees: Dr. Scient in immunogenetics, Norwegian College of Veterinary Medicine, Oslo 1992.
 
Professional background:  Research fellow at Norwegian College of Veterinary Medicine (1988 – 1992). Scientist at Norwegian College of Veterinary Medicine (1992 – 1994). Scientist at Norwegian University of Life Sciences (1994 – 2000). Senior Adviser in medical use of biotechnology (2000 – 2002), Norwegian Directorate for Health and Social Affairs. Director R&D, BoviBank, (2002 – 2003). Professor at the Department of Animal- and Aquacultural Sciences, UMB (2003-).

Current research activity: Mapping and molecular characterisation of single and multi locus traits in diverse animal species. Chair of the “Genofisk” project: CIGENE-PWP1: “Identification of the genetic determinants underlying fillet pigmentation in salmon”, using both genomic and proteomic tools. Mapping genes related to stress coping style in salmonids. Investigating the genetic background for muscle development, carotenoid metabolism and lamb mortality in sheep.

Current teaching activity: Responsible for the courses HFM200, BIO322 and BIN 350.

Other activities: Board member at the Department of Animal- and Aquacultural Sciences (2005-). Research group leader at Department of Animal- and Aquacultural Sciences (2005-). Deputy head of department (2007-2008). Board member of “FUGE-East”, National program on functional genomics (2005-2008). Member of advisory committee on “conservation and sustainable use of national genetic resources in farm animals” (Genressursutvalget). (2006-). Member of advisory committee on “bio- and gene technology”, Norwegian Directorate for Health and Social Affairs (2007-).

Selected publications:

  • Våge DI, Olsaker I, Lingaas F, Spooner RL, van der Beek S, Sørensen A, Arnet EF and Lie Ø (1992) High levels of linkage disequilibria between serologically defined class I bovine lymphocyte antigens (BoLA-A) and class II DQB restriction fragment length polymorphism (RFLP) in Norwegian cows. Animal Genetics 23, 125-32.
  • Klungland  H, Våge DI, Raya LG, Adalsteinsson S and Lien S (1995) The role of melanocyte-stimulating hormone (MSH) receptor in bovine coat color determination. Mammalian Genome 6, 636-39.
  • Våge DI, Lu D, Klungland H, Lien S, Adalsteinsson S and Cone RD (1997) A non-epistatic interaction of agouti and extension in the fox, Vulpes vulpes. Nature Genetics 15, 311-15.
  • Lu D, Våge DI and Cone RD (1998) A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor. Molecular Endocrinology 12 , 592-604.
  • Våge DI, Klungland H, Lu D and Cone RD (1999) Molecular and pharmacological characterization of dominant black coat color in sheep.  Mammalian Genome 10, 39-43.
  • Lien S, Karlsen AM, Klemetsdal G, Våge DI, Olsaker I, Klungland H, Aasland M, Heringstad B, Ruane J and Gomez-Raya L (2000) A primary screen of the bovine genome for quantitative trait loci affecting twinning rate. Mammalian Genome 11, 877-82.
  • Klungland H, Sabry A, Heringstad B, Olsen HG, Gomez Raya  L, Våge DI, Olsaker I, Ødegård J, Klemetsdal G, Schulman N, Vilkki J, Ruane J, Aasland M, Rønningen K and Lien S (2001) Quantitative trait loci affecting clinical mastitis and somatic cell count in dairy cattle. Mammalian Genome, 12, 837-42.
  • Gomez Raya  L, Olsen HG, Lingaas F, Klungland H, Våge DI,  Olsaker I, Talle SB, Aasland M and Lien S (2002) The use of genetic markers to measure genomic response to selection in livestock. Genetics 162, 1381-8.
  • Våge DI, Fleet MR, Ponz R, Olsen RT, Monteagudo LV, Tejedor MT, Arruga MV, Gagliardi R, Postiglioni A, Nattrass GS  and Klungland H  (2003) Mapping and Characterization of the Dominant Black Colour Locus in Sheep. Pigment Cell Research 16, 693–97.
  • Våge DI, Fuglei E, Snipstad K, Beheim J, Landsem VM and Klungland H (2005) Two cysteine substitutions in the MC1-R generate the blue variant of the arctic fox (Alopex lagopus) and prevent expression of the white winter coat. Peptides 26, 1814–17
  • Rajasingh H, Øyehaug L, Våge DI and Omholt S (2006) Carotenoid dynamics in Atlantic salmon. BMC Biology 4, 10.
  • Opsal MA, Våge DI, Hayes B, Berget I and Lien S (2006) Genomic organization and transcript profiling of the bovine toll-like receptor gene cluster TLR6-TLR1-TLR10. Gene, 384, 45-50.
  • Rajasingh H, Våge DI, Pavey SA and Omholt S (2007) Why are salmonids pink? Canadian Journal of Fisheries and Aquatic Sciences, 64, 1614-27  
  • Opsal MA, Lien S, Brenna-Hansen S, Olsen HG, Våge DI (2008) Association analysis of the constructed linkage maps covering TLR2 and TLR4 with clinical mastitis in Norwegian Red cattle. Journal of Animal Breeding and Genetics 125, 110-8.
  • Rajasingh H, Gjuvsland A, Våge DI & Omholt SW (2008) When parameters in dynamic models become phenotypes - a case study on flesh pigmentation in the Chinook salmon. Genetics 179, 1113-8.
  • Boman IA, Klemetsdal G, Blichfeldt T, Nafstad O & Våge DI (2009) A frameshift mutation in the coding region of the myostatin gene (MSTN) affects carcass conformation and fatness in Norwegian White Sheep (Ovis aries). Animal Genetics 40, 418-22.
  • Boman IA & Våge DI (2009) An insertion in the coding region of the myostatin (MSTN) gene affects carcass conformation and fatness in the Norwegian Spaelsau (Ovis aries). BMC Research Notes 2, 98.