Arne GjuvslandGjuvsland, Arne Bjørke

Postdoc

E-mail: arne.gjuvsland@umb.no

Phone: +47-6496-5292

Present positions: Postdoctoral fellow at CIGENE/IMT, UMB.

Degrees: PhD in systems biology at the Norwegian University of Life Sciences (UMB), 2007. Cand.scient. in applied mathematics at the Agricultural University of Norway (NLH), 2003.
   
Professional background: Postdoctoral fellow, Cigene/IMT, UMB (2007-); PhD student, Cigene/IHA, UMB (2004-2007); Research assistant, Cigene/IHA, UMB (2003-2004).

Research experience: Development and application of virtual genome platform, connection between nonlinear system dynamics and genetics, and generic robustness features of complex systems.

Current research activity: I work in the eVITA project "Bridging the gap: disclosure, understanding and exploitation of the genotype-phenotype map" on the heart model and yeast work packages. I'm involved in a range of activities aimed at bridging quantitative genetics with regulatory biology through mathematical analysis, simulations and experiments. My work is focused on building and analyzing causally-cohesive genotype phenotype (cGP) models of biological systems.

Publications:

  • Gjuvsland A, Vik J, Wooliams J, Omholt S. (2011) Order-preserving properties of genotype-phenotype maps and regulatory systems ensure high additive genetic variance. Journal of Evolutionary Biology 24(10):2269-2279 [ fulltext ]
  • Kristin Tøndel, Ulf G. Indahl, Arne B. Gjuvsland, Jon Olav Vik, Ingunn Berget, Peter Hunter, Stig W. Omholt and Harald Martens (2011) Hierarchical Local Partial Least Squares Regression is an efficient tool for metamodelling of nonlinear dynamic models. BMC Systems Biology 5:90 [ fulltext ]
  • Jonas Warringer, Enikö Zörgö, Francisco Cubillos, Amin Zia, Arne Gjuvsland, Richard Durbin, Stig W. Omholt, Edward J. Louis, Gianni Liti, Alan Moses, Anders Blomberg (2011) Trait variation in yeast is defined by population history. PLoS Genetics 7(6):e1002111 [ fulltext ]
  • Kristin Tøndel, Arne B. Gjuvsland, Ingrid Måge, Harald Martens (2010) Screening design for computer experiments: metamodelling of a deterministic mathematical model of the mammalian circadian clock Journal of Chemometrics 24(11-12): 738-747 [ fulltext ]
  • Gjuvsland AB, Plahte E, Ådnøy T, Omholt SW (2010) Allele Interaction - Single Locus Genetics Meets Regulatory Biology. PLoS ONE 5(2):e9379 [ fulltext ]
  • Rajasingh H. et al (2008) When parameters in dynamic models become phenotypes:a case study on flesh pigmentation in the Chinook salmon (Oncorhynchus tshawytscha). Genetics 179:1113–1118 [ fulltext ]
  • Gjuvsland, A. et al. (2007). Threshold-dominated regulation hides genetic variation in gene expression networks. BMC Systems Biology 1:57     [ fulltext ]
  • Gjuvsland, A. et al. (2007). Nonlinear regulation enhances the phenotypic expression of trans-acting genetic polymorphism. BMC Systems Biology 1:32 [ fulltext ]
  • Gjuvsland, A. et al. (2007). Statistical epistasis is a generic feature of gene regulatory networks. Genetics 175: 411-420 [ fulltext ]
  • Hayes, B. et al. (2006). Power of QTL mapping experiments in commercial Atlantic salmon populations, exploiting linkage and linkage disequilibrium and effect of limited recombination in males. Heredity 97: 19-26 [ fulltext ]