Achim KohlerKohler, Achim

Associate Professor

E-mail: achim.kohler@umb.no

Phone: +47-6496-6174

Present positions: Associate Professor at the Dept. of Mathematics and Technology (IMT) and CIGENE, Norwegian University of Life Sciences;  research scientist (20%) at Nofima Mat.

Degrees: M.Sc in physics and Dr. rer. nat. in theoretical physics at the Albert-Ludwigs University of Freiburg, Department of Physics, Germany.

Previous experience in directing research: Began scientific career in theoretical physics and data modelling of complex quantum systems. Over the last 10 years have been working as a biospectroscopist at Campus Ås with a strong focus on data analysis. With a main research focus on the development of spectroscopic methods for the characterisation of cells and tissues. Have also contributed significantly to the development of data analytical tools in modern vibrational spectroscopy.

Present research activities and fields of interest: Present research interests include
a) development of high-throughput vibrational spectroscopy tools for the characterisation of cells and other biological material.
b) modelling of light scattering effects as in biospectroscopy;
c) new integrative data analytical methods for functional genomics;

Additional information: http://arken.umb.no/~achik/

Selected publications:
  • Oust Janbu A, Møretrø T, Bertrand D, Kohler A (2008) FTIR microspectroscopy: a promising method for rapid identification of Listeria species. FEMS Microbiology Letters, 278, 164.-170.
  • Kohler A, Sulé-Suso J, Sockalingum GD, Tobin M, Bahrami F, Yang Y, Pijanka J, Dumas P, Cotte M, Martens H (2008) Estimating and correcting Mie scattering in synchrotron based microscopic FTIR spectra by extended multiplicative signal correction (EMSC). Applied Spectroscopy , 62, 259-266.
  • Böcker U, Kohler A, Aursand IG, Veliyulin E, Egelandsdal B, Ofstad R (2008) Effects of brine salting with regards to raw material variation of Atlantic salmon (Salmo salar) muscle investigated by FTIR microspectroscopy. J. Agric. Food Chem. 56, 5129-5137.
  • Trosvik P, Rudi K, Naes T, Kohler A, Chan KS, Jakobsen KS, Stenseth NC (2008), Characterizing mixed microbial population dynamics using time-series analysis. ISME Journal 2 (7), 707-15.
  • Håseth T, Høy M, Kongsro J, Kohler A, Sørheim O, Egelandsdal B (2008) Determination of sodium chloride in pork meat by computed tomography at different voltages. Journal of Food Science 73 (7), 333-339.
  • Kohler A, Böcker U, Warringer J, Blomberg A, Omholt SW, Stark E, Martens H (2009) Reducing inter-replicate variation in Fourier-transform infrared spectroscopy by extended multiplicative signal correction. Applied spectroscopy 63 (3), 296-305.
  • Pijanka J, Kohler A, Sockalingum GD, Yang Y, Dumas P, Nicholson J, Chio-Srichan SM, Manfait M, Sockalingum GD, Sulé-Suso J (2009) Spectroscopic Signatures of Single, Isolated Cancer Cell Nuclei using Synchrotron Infrared microscopy. Analyst 134, 1176 – 1181.
  • Segtnan VH, Høy M, Sørheim O, Kohler A, Lundby F, Wold JP, Ofstad R (2009) Non-contact salt and fat distributional analysis in salted and smoked salmon fillets using X-ray computed tomography and NIR interactance imaging. J. Agric. Food Chem. 57 (5), 1705–1710.
  • Carton I, Böcker U, Ofstad R, Sørheim O, Kohler A (2009) Monitoring secondary structural changes in salted and smoked salmon muscle myofiber proteins by FTIR microspectroscopy. J. Agric. Food Chem. 57, 3563–3570.
  • Moen B, Janbu A, Langsrud S, Langsrud Ø, Hobman J L, Constantinidou C, Kohler A, Rudi K (2009) Global responses of Escherichia coli to adverse conditions determined by microarrays and FTIR spectroscopy. Canadian Journal of Microbiology 55 (6) 714-728.
  • Martens H, Kohler A (2009) Mathematics and measurements for high-throughput quantitative biology. Biological Theory, Special issue on Quantifying Biology. Biological Theory 4 (1), 29-43.
  • Tessema GT, Møretrø T, Kohler A, Axelsson L, Naterstad K (2009) Complex phenotypic and genotypic responses of Listeria monocytogenes strains exposed to the class IIa bacteriocin Sakacin P. Applied and Environmental Microbiology 75 (22), 6973-6980.
  • Bassan P, Kohler A, Martens H, Lee J, Byrne H J, Dumas P, Gazi E, Brown M, Clarke N, Gardner P (2010) Resonant Mie Scattering (RMieS) Correction of Infrared Spectra from Highly Scattering Biological Samples, Analyst 135, 268–277.
  • Berget I, Martens H, Kohler A, Sjurseth SK, Afseth NK, Bjørg Narum, Ådnøy T, Lien S (2010), Caprine csn1s1 haplotype effect on gene expression and milk composition measured by FTIR spectroscopy. Journal of Dairy Science, 93 (9), 4340-4350.
  • Pijanka J, Sockalingum G D, Kohler A, Yang Y, Draux F, Parkes G, Lam K.-P., Collins D, Dumas P, Sandt C, van Pittius D G, Douce G, Manfait M, Untereiner V, Sulé-Suso J (2010) Synchrotron based FTIR spectra of stained single cells. Towards a clinical application in pathology. Laboratory Investigation 90, 797-807.
  • Pijanka J K, Stone N, Cinque G, Yang Y, Kohler A, Wehbe K, Frogley M, Parkes G, Parkes J, Dumas P, Sandt C, van Pittius D G, Douce G, Sockalingum GD, Sulé-Suso J (2010) FTIR microspectroscopy of stained cells and tissues. Application in cancer diagnosis. Spectroscopy 24, 73-78.
  • Shapaval V, Møretrø T, Suso HP, Wold Åsli A, Schmitt J, Lillehaug D, Martens H, Böcker U, Kohler A (2010) A high-throughput microcultivation protocol for FTIR spectroscopic characterization and identification of fungi. Biophotonics Journal 3 (8-9), 512-521.
  • Bassan, P, Kohler, A, Martens, H, Lee, J, Byrne, H, Gardner, P (2010) The RMieS-EMSC correction algorithm for infrared spectra of biological cells: Extension using full Mie scattering theory and speed optimisation using graphics processing unit (GPU) computing. Biophotonics Journal 3 (8-9), 609-620.
  • Afseth NK, Martens H, Giskehaug L, Narum B, Jørgensen K, Lien S, Haug A, Kohler A (2010) Predicting fatty acid composition of milk - A comparison of two FTIR sampling techniques. Applied Spectroscopy 64 (7), 700-707.
  • Adt I, Kohler A, Gognies S, Budin J, Sandt C, Belarbi A, Manfait M, Sockalingum G D (2010) FTIR spectroscopic discrimination of S. Cerivisiae and S. Bayanus strains. Canadian Journal of Microbiology 56 (9), 793–801.
  • Hassani S, Martens H, Qannari M, Hanafi M, Borge G I, Kohler A (2010) Analysis of –omics data: Graphical interpretation- and validation tools in multi–block methods. Chemometrics and Intelligent Laboratory Systems 104, 140-153.
  • Calvez S, Kohler A, Prévost H, Møretrø T, Drider D (2010) Physiological and structural differences between Enterococcus faecalis JH2-2 and variants strains resistant to divercin RV41. Probiotics and Antimicrobial Proteins 2 (4) 226.
      Book chapters:
  • Kohler A, Hanafi M, Bertrand D, Oust Janbu A, Møretrø T, Naderstad K, Qannari M, Martens H (2008) Interpreting several types of measurements in bioscience, in: Modern concepts in biomedical vibrational spectroscopy, John Wiley & Sons, USA, Editors: Lasch P, Kneipp J, 333-356.
  • Færgestad EM, Langsrud Ø, Høy M, Hollung K, Sæbø S, Liland KH, Kohler A, Gidskehaug L, Almergren J, Anderssen E, Martens H (2009) Analysis of Megavariate Data in Functional Genomics, in: Comprehensive Chemometrics, Elsevier, Oxford, UK, Editors: Brown S, Tauler R, Walczak R , volume 4, 221-278.
  • Kohler A, Zimonja M, Segtnan V, Martens H (2009) Data preprocessing: SNV, MSC and EMSC pre-processing in biospectroscopy, in: Comprehensive Chemometrics, Elsevier, Oxford, UK, Editors: Brown S, Tauler R, Walczak R, volume 2, 139-162.
  • Kohler A, Afseth NK, Jørgensen K, Randby Å, Martens H (2010) Quality analysis of milk by vibrational spectroscopy, in: Applications of Vibrational Spectroscopy in Food Science, John Wiley & Sons Ltd , Chichester, UK, Editors: Chalmers J, Li-Chan E, Griffiths P R, 483-500.
  • Kohler A, Afseth NK, Martens H (2010) Chemometrics in biospectroscopy in: Applications of Vibrational Spectroscopy in Food Science, John Wiley & Sons Ltd , Chichester, UK, Editors: Chalmers J, Li-Chan E, Griffiths PR, 89-108.