On Tuesday June 14 Dr. Marit Holden, senior research scientist at the Norwegian Computing Centre in Oslo, will give a talk on logic regression in statistical analysis of SNP data.
Time: Tuesday 14 June, 11.15 - 12.00Place: Norwegian University of Life Sciences (UMB), Biotechnology Building, room BT3A-16.
 Lecture 14 June: Logic regression used for statistical analysis of SNP data obtained in genetic association studies |
in the case when most covariates are binary, like in the SNP case. Statistical methods for finding SNPs associated with disease are often based on hypothesis testing, where each SNP is tested separately. Such methods ignore the multigenic nature of complex traits and possible interactions between susceptibility genes. Logic regression is one method where such interactions are taken into account, and where the SNPs are analyzed jointly, rather than tested one by one.
In the talk Marit Holden will present the logic regression technique, and show how it has been applied to SNP data for suggesting associations between groups of SNPs and some response (for example disease status).
More information on Dr. Holden's work can be found here
